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Collanet Labs

Extracellular matrix preparations, with
special emphasis on Collagen Type II
(chicken sternae).

E mail: gelux@operamail.com

Collagen Type II
Cat. # PM 1938-40

Source: 4-6 week old chicken sternae

Introduction / Use

For rheumatic arthritis and platelet aggregation research.

Oral tolerization of the undenatured collagen type II, as dietary supplement. 

Extraction and Purification

By nonconventional methodology avoiding the utilization of pepsin, to obtain the native conformation as much as possible, rendering a T Cell Proliferation Assay Grade and higher immunogenicity. Purification by ion chromatography and/or preparative electrophoresis to facilitate critical separations of noncollagenous contaminants.

Purity Analysis

Type II profile by SDS-PAGE, with/without -SH reduction, using collagen types I, II, III, IX, and XI as molecular weight standards. To detect proteoglycans, using glucuronolactone as standard, uronic acid analysis is performed. To detect non-collagen protein contaminants, BCA protein test is done. Results in a purity over 95%.

Presentation

Lyophilized from 0.1% acetic acid, or solution of 0.4% in 0.4% acetic acid.

Storage

Refrigerate at 2-8 (degrees). The solution at -20(degrees) for up to 6 months.

Availability

In a wide range of quantities.

Note

Cat. # TM 1938-44 obtained by a modified Trentham method (Trentham, et al., J. of Exp. Med. 146:857-868) is also available in the same range of purity and presentation.

Special Orders

Special orders can be prepared for any type of collagens.

Electrophoresis profiles of collagens provided too.

Biotech Holdings • Gelux, Inc.

European Branch: Bucharest  - ROMANIA - EU

American Branch : Akron - OHIO - USA


E mail alternative:    gelux@msn.com

geluxusa@netscape.net

Peter Lugojan, Ph.D.                      
Chairman • CEO • Res. Dir.                   
Michelle Lugojan
President
Copyright ©1998 Biotech Holdings, Inc.

Updated:February 22, 2008